Flavin adenine dinucleotide disodium salt hydrate

SIGMA/F6625 - ≥95% (HPLC), powder

Synonym: FAD; FAD-Na2; Riboflavin 5′-adenosine diphosphate disodium salt; FAD; FAD-Na₂; Riboflavin 5′-adenosine diphosphate disodium salt

CAS Number: 84366-81-4 (anhydrous)
Empirical Formula (Hill Notation): C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
Molecular Weight: 829.51 (anhydrous basis)
MDL Number: MFCD08277021
Linear Formula: C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F6625-10MG	10 mg	$76.10 1/EA	Add To Favorites
45-F6625-25MG	25 mg	$86.80 1/EA	Add To Favorites
45-F6625-100MG	100 mg	$155.00 1/EA	Add To Favorites
45-F6625-250MG	250 mg	$258.00 1/EA	Add To Favorites
45-F6625-500MG	500 mg	$451.00 1/EA	Add To Favorites
45-F6625-1G	1 g	$776.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6625-100MG

Properties
Descriptions
Safety Info.
Basic Data

λ_max	375-377 nm
	448-450 nm
assay	≥95% (HPLC)
biological source	microbial
color	yellow to orange-brown
fluorescence	(EmM Anhydrous 10.5 - 11.8 pH 7.0, Lambda Max 448 to 450 nm EmM Anhydrous 8.5 - 9.5 pH 7.0, Lambda Max 375 to 377 nm)
form	powder
InChI	1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
InChI key	GXTPHHZYFMAGLX-UJXBNFGUSA-L
mol wt	829.51 g/mol
Quality Level	200
SMILES string	[Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C
solubility	H₂O: soluble-50 mg/mL, clear, slightly orang to deep orange
storage temp.	−20°C

Application:	FAD is used to remove reactive oxygen species (ROS) from mammalian cells. The fluorescence mechanism of FAD is used to study energy-dependent intramitochondrial redox potential. FAD is used as a predominant fluorophore to study unstained eosinophils, which exhibit autofluorescence compared to other leucocytes.
Application:	Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.
General description:	Flavin adenine dinucleotide disodium salt hydrate (FAD-Na2) is an adenine-containing enzymatic redox cofactor. Also known as flavin cofactors, FAD is critical electron transporter in living systems. They catalyze several 1-2 electron redox reactions. e.g., β-oxidation of fatty acids occurs in the presence of FAD as a cofactor. FAD is one of the two active coenzymes of vitamin B12(riboflavin). FAD displays a significantly shorter excited state lifetime in aqueous solutions than its analog, flavin mononucleotide.
Packaging:	1 g in poly bottle
Packaging:	10, 25, 100, 250, 500 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	41106305

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