Riboflavin 5′-monophosphate sodium salt hydrate

SIGMA/F6750 - 70-79% (fluorimetric)

Synonym: FMN-Na; Flavin mononucleotide; Riboflavin 5′-phosphate sodium salt

CAS Number: 130-40-5 (anhydrous)
Empirical Formula (Hill Notation): C₁₇H₂₀N₄NaO₉P · xH₂O
Molecular Weight: 478.33 (anhydrous basis)
MDL Number: MFCD00150992
Linear Formula: C₁₇H₂₀N₄NaO₉P · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F6750-5G	5 g	$90.80 1/EA	Add To Favorites
45-F6750-25G	25 g	$156.00 1/EA	Add To Favorites
45-F6750-100G	100 g	$395.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6750-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	70-79% (fluorimetric)
biological source	non-animal source
description	(Clear to hazy)
form	powder
InChI	1S/C17H21N4O9P.Na.H2O/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);;1H2/q;+1;/p-1/t11-,12+,14-;;/m0../s1
InChI key	BHRVCJBIICJWTH-APQIITSESA-M
Quality Level	200
SMILES string	O.[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C
solubility	water: 50 mg/mL, orange
storage temp.	−20°C

Analysis Note:	Free Riboflavin: ≤6.0% Riboflavin diphosphates: ≤6.0% (as riboflavin)
Application:	Riboflavin 5′-monophosphate is used as a substrate to study the specificity and kinetics of FMN phosphohydrolases. FMN is used to study molecular sensing based gene regulation by riboswitches.
Application:	Riboflavin 5′-monophosphate sodium salt hydrate has been used in the preparation of hypo-osmolar riboflavin formulation: • to evaluate the riboflavin (RF) concentration and distribution in the corneal stroma • to study corneal resistance to enzymatic digestion • as a photosensitizer to evaluate the efficacy and safety of photochemical corneal stiffening using ex vivo and in vivo rabbit eye models
Biochem/physiol Actions:	Riboflavin 5′-monophosphate (FMN) serves as a cofactor for flavoenzymes. It is used as a prosthetic group by oxidoreductase (one and two-electron transfer) enzymes, also called flavoproteins, such as nicotinamide adenine dinucleotide (NADH) dehydrogenases, nitric oxide synthases, nitric oxide reductase, and nitrilotriacetate monooxygenases. These enzymes protect cells from oxidative stress and apoptosis. Any alteration in the levels of FMN caused due to abnormal riboflavin metabolism leads to mitochondrial dysfunction and diminished energy levels. This results in disorders related to riboflavin such as cataracts, neurodegenerative and cardiovascular diseases. FMN is associated with metabolic pathways of amino acids, fatty acids, and purines. It is involved in cellular growth and development mediated by the oxidation-reduction reaction.
General description:	Riboflavin 5′-monophosphate is a derivative of riboflavin, a water-soluble vitamin.
Packaging:	5, 25, 100 g in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	70-79% (fluorimetric)
Storage Temp.	−20°C
UNSPSC	41106305

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