Fumagillin from Aspergillus fumigatus

SIGMA/F6771 - ≥90%, powder

Synonym: Fugillin

CAS Number: 23110-15-8
Empirical Formula (Hill Notation): C₂₆H₃₄O₇
Molecular Weight: 458.54
EC Number: 245-433-8
MDL Number: MFCD03990453
Linear Formula: C₂₆H₃₄O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-F6771-1MG	1 mg	$306.00 1/EA		Add To Favorites
45-F6771-5MG	5 mg	$1270.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	fungi
assay	≥90%
biological source	Aspergillus sp. (Aspergillus fumigatus)
color	white
form	powder
InChI	1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+
InChI key	NGGMYCMLYOUNGM-HCNIIHBUSA-N
mode of action	DNA synthesis \| interferes
mp	197-198 °C
Quality Level	200
SMILES string	COC1C(CCC2(CO2)C1C3(C)OC3CC=C(C)C)OC(=O)C=CC=CC=CC=CC(O)=O
solubility	ethanol: 1 mg/mL
storage temp.	−20°C

Application:	Fumagillin from Aspergillus fumigatus has been used: • in chick chorioallantoic membrane (CAM) assay to study the changes in protein expression in response to anti-angiogenic agent • to study its effects on the mortality of caged Nosema ceranae-infected honey bees- write in this way • as a positive control in in vitro and ex vivo studies
Biochem/physiol Actions:	Fumagillin is known to be effective against microsporidian fungal infections.
Biochem/physiol Actions:	Methionine aminopeptidase-2 (MetAP-2) inhibitor; inhibits endothelial cell proliferation and angiogenesis.
General description:	Fumagillin is a metabolic product of fungi. It is originally isolated from Aspergillus fumigatus.
Packaging:	1, 5 mg in serum bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
Safety Statements	36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90%
mp	197-198 °C
Storage Temp.	−20°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.