5-Fluorocytosine
SIGMA/F7129 - nucleoside analog
Synonym: 4-
CAS Number: 2022-85-7
Empirical Formula (Hill Notation): C4H4FN3O
Molecular Weight: 129.09
EC Number: 217-968-7
MDL Number: MFCD00006035
Linear Formula: C4H4FN3O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7129-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7129-5G
| λmax | 285-287 nm |
| antibiotic activity spectrum | fungi |
| assay | ≥99% (TLC) |
| color | white to off-white |
| concentration | ≤100% (Flucytosine) |
| fluorescence | (EmM Anhydrous 8.8 - 9.4, pH 1.0) |
| form | powder |
| InChI | 1S/C4H4FN3O/c5-2-1-7-4(9) |
| InChI key | XRECTZIEBJDKEO-UHFFFAOYSA |
| mode of action | DNA synthesis | interferes |
| protein synthesis | interferes | |
| mol wt | 129.09 g/mol |
| mp | 298-300 °C (dec.) (lit.) |
| Quality Level | 200  |
| SMILES string | NC1=NC(=O)NC=C1F |
| solubility | formic acid: 50 mg/mL, colorless to faintly yellow |
| storage temp. | 2-8°C |
| Application: | Used in studies on TMP biosynthesis. |
| Biochem/physiol Actions: | Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis. |
| General description: | Chemical structure: nucleoside |
| Packaging: | 1, 5 g in poly bottle |
| Symbol |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P281 |
| Hazard Codes | Xn |
| Risk Statements | 63 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (TLC) |
| mp | 298-300 °C (dec.) (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |