Fosmidomycin sodium salt hydrate
SIGMA/F8682 - ≥95% (NMR)
Synonym: (3-
CAS Number: 66508-53-0 (free base)
Empirical Formula (Hill Notation): C4H10NO5P · xNa+ · yH2O
Molecular Weight: 183.10 (anhydrous free acid basis)
MDL Number: MFCD00865023
Linear Formula: C4H10NO5P · xNa+ · yH2O
Product Type: Chemical
| assay | ≥95% (NMR) |
| color | white to beige |
| form | powder |
| InChI | 1S/C4H10NO5P/c6-4-5(7)2-1 |
| InChI key | GJXWDTUCERCKIX-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [P](=O)(O)(O)CCCN(O)C=O |
| solubility | H2O: 20 mg/mL, clear |
| storage condition | desiccated |
| storage temp. | −20°C |
| Application: | Fosmidomycin sodium salt hydrate has been used as an inhibitor of 1-deoxy- |
| Biochem/physiol Actions: | Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. |
| Biochem/physiol Actions: | Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (NMR) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |