Formaldehyde solution
SIGMA/F8775 - Molecular Biology, 36.5-38% in H2O
Synonym: Formalin
CAS Number: 50-00-0
Empirical Formula (Hill Notation): CH2O
Molecular Weight: 30.03
EC Number: 200-001-8
MDL Number: MFCD00003274
Linear Formula: HCHO
Product Type: Chemical
| application(s) | general analytical genomic analysis |
| autoignition temp. | 572 °F |
| concentration | 36.5-38% in H2O |
| contains | 10-15% methanol |
| density | 1.09 g/mL at 25 °C (lit.) |
| form | liquid |
| grade | Molecular Biology |
| InChI | 1S/CH2O/c1-2/h1H2 |
| InChI key | WSFSSNUMVMOOMR-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [H]C([H])=O |
| storage temp. | 15-25°C |
| suitability | suitable for (use in Formaldehyde-Agarose Gel Electrophoresis of RNA) |
| technique(s) | ChIP: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| vapor density | 1.03 (vs air) |
| vapor pressure | 52 mmHg ( 37 °C) |
| Analysis Note: | Tested for use in formaldehyde-agarose gel electrophoresis of RNA. |
| Application: | Formaldehyde solution has been used for fixing of cells and tissue sections. It has been used in the formaldehyde agarose gel electrophoresis. Formaldehyde is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA. |
| Features and Benefits: | • Versatile and adaptable for a wide variety of laboratory and research applications • Suitable for Molecular Biology and Biochemical applications |
| General description: | Formaldehyde, a colorless, pungent-smelling chemical, finds extensive application in various biological research and laboratory settings. Primarily supplied as a 37% solution (formalin), its diverse uses range from tissue preservation and sterilization to acting as a denaturant in RNA gel electrophoresis. However, it′s crucial to acknowledge its potential health risks and handle it with appropriate precautions.Multifaceted Functions: • Preservative: Formaldehyde′s ability to inhibit microbial growth makes it an effective preservative in biological samples, preventing decay and ensuring their integrity for further analysis. This property finds application in medical laboratories, museums, and even embalming fluids. • Fixative: In histology, formaldehyde acts as a fixative, cross-linking proteins and preserving tissue structures for microscopic examination. This allows researchers to visualize anatomical details and cellular components with remarkable clarity. • Denaturant: In molecular biology techniques like formaldehyde-agarose gel electrophoresis, formaldehyde denatures RNA molecules, preventing them from forming secondary structures and enabling size-based separation. This technique proves invaluable for studying gene expression and RNA integrity. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research  |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 25, 500 mL in poly bottle |
| Symbol |     GHS02,GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H226 - H301 + H311 - H314 - H317 - H330 - H335 - H341 - H350 - H370 |
| Precautionary statements | P201 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 45-23/24/25-34-39/23/24/25-43-68 |
| Safety Statements | 53-26-36/37/39-45 |
| RIDADR | UN 2209 8 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 133.0 °F - closed cup |
| Flash Point(C) | 56.11 °C - closed cup |
| Density | 1.09 g/mL at 25 °C (lit.) |
| Storage Temp. | 15-25°C |
| UNSPSC | 12352114 |