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Flupirtine maleate salt

SIGMA/F8927 - ≥98% (HPLC)

Synonym: 2-Amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid ethyl ester maleate salt

CAS Number: 75507-68-5
Empirical Formula (Hill Notation): C15H17FN4O2 · C4H4O4
Molecular Weight: 420.39
MDL Number: MFCD00941415
Linear Formula: C15H17FN4O2 · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F8927-5MG 5 mg
 $145.00
1/EA		 Add To Favorites
45-F8927-25MG 25 mg
 $495.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts F8927-25MG

 

assay ≥98% (HPLC)
color white
form solid
InChI 1S/C15H17FN4O2.C4H4O4/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10;5-3(6)1-2-4(7)8/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key DPYIXBFZUMCMJM-BTJKTKAUSA-N
Quality Level 100 
SMILES string OC(=O)C=C/C(O)=O.CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N
solubility DMSO: soluble >20 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Biochem/physiol Actions: Flupirtine is commercially available as maleate salt. It exists in two polymorphs : flupirtine maleate A and B. Flupirtine is useful in treating muscular spasm, muscle tension and muscle stiffness. It is known to be effective in relieving back pain. Along with cytoprotection, flupirtine also offers protection against neurodegenerative disorders such as multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer′s disease, Parkinson′s disease, Huntington′s chorea and AID (acquired immunodeficiency) associated encephalopathy. Flupirtine is found to be a potential drug for eye-related problems like maculopathy including diabetic retinopathy, retinitis pigmentosa and glaucoma. It is also proved to be helpful in preventing cardiac associated disorders such as myocardial ischemia and infarction, cerebral ischemia and infarction. Hepatitis is also prevented by the use of flupirtine.
Biochem/physiol Actions: Non-opioid analgesic; cytoprotective versus PrP fragment 106-126
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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