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Fluorometholone

SIGMA/F9381 - ≥98%

Synonym: 11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

CAS Number: 426-13-1
Empirical Formula (Hill Notation): C22H29FO4
Molecular Weight: 376.46
EC Number: 207-041-5
MDL Number: MFCD00056461
Linear Formula: C22H29FO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F9381-100MG 100 mg
 $161.00
1/EA		 Add To Favorites
45-F9381-500MG 500 mg
 $427.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: F9381-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: F9381-500MG

 

assay ≥98%
InChI 1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
InChI key FAOZLTXFLGPHNG-KNAQIMQKSA-N
Quality Level 200 
SMILES string C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)[C@@]4(C)C=CC(=O)C=C14
Application:

  • Topical fluorometholone treatment and desiccating stress change inflammatory protein expression in tears.: This research explores the changes in tear protein expression due to topical fluorometholone and environmental stress, offering insights into ocular surface inflammatory responses (Nättinen et al., 2018 ).

  • General Pharmacokinetic Model for Topically Administered Ocular Drug Dosage Forms.: This study provides a pharmacokinetic model applicable to topical ocular medications, including fluorometholone, enhancing understanding of drug dynamics in eye treatments (Deng et al., 2016 ).
Biochem/physiol Actions: Clinically significant in allergic conjunctivitis and as anti-inflammatory following cataract surgery.
Packaging: 100, 500 mg in poly bottle
Purity ≥98%
UNSPSC 12352212

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