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Fexofenadine hydrochloride

SIGMA/F9427 - >98% (HPLC)

Synonym: Fexofenidine hydrochloride; MDL 16455 hydrochloride; Terfenidine carboxylate hydrochloride

CAS Number: 153439-40-8
Empirical Formula (Hill Notation): C32H39NO4 · HCl
Molecular Weight: 538.12
MDL Number: MFCD00865710
Linear Formula: C32H39NO4 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F9427-10MG 10 mg
 $205.00
1/EA		 Add To Favorites
45-F9427-50MG 50 mg
 $727.00
1/EA		 Add To Favorites

 

assay >98% (HPLC)
color white to beige
form powder
InChI 1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H
InChI key RRJFVPUCXDGFJB-UHFFFAOYSA-N
originator Sanofi Aventis
Quality Level 100 
SMILES string Cl[H].CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4
solubility DMSO: soluble ≥5 mg/mL
storage condition desiccated
storage temp. −20°C
Application: Fexofenadine hydrochloride has been used as a non-cationic ampliphilic antihistamines in NCI-H661 cells and as a histamine H1 receptor antagonist in mice
Biochem/physiol Actions: Fexofenadine is a non-sedating H1 histamine receptor antagonist.
Biochem/physiol Actions: Fexofenadine is used in treating allergic rhinitis and chronic idiopathic urticaria. It may give relief in bothersome symptom and is a second-generation antihistamines. Fexofenadine provides better relief compared to other antihistamines for nasal congestion. It is the active metabolite of terfenadine and bring down allergen-induced symptoms.
Features and Benefits: This compound is a featured product for ADME Tox research. Click here  to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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