Synonym: (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester
CAS Number: 80474-14-2
Empirical Formula (Hill Notation): C25H31F3O5S
Molecular Weight: 500.57
MDL Number: MFCD00866007
Linear Formula: C25H31F3O5S
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white |
| form |
powder |
| InChI |
1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1 |
| InChI key |
WMWTYOKRWGGJOA-CENSZEJFSA-N |
| originator |
GlaxoSmithKline |
| Quality Level |
100  |
| SMILES string |
CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF |
| solubility |
DMSO: ≥10 mg/mL |
| Biochem/physiol Actions: |
Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor. |
| Features and Benefits: |
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: |
This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: |
Fluticasone blocks mast cells, eosinophils, lymphocytes, neutrophils and macrophages. |
| Packaging: |
5 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 2 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| UNSPSC |
12352200 |
