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Formoterol fumarate dihydrate

SIGMA/F9552 - >98% (HPLC)

Synonym: (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate; Formoterol hemifumarate salt monohydrate

CAS Number: 183814-30-4
Empirical Formula (Hill Notation): C19H24N2O4 · 0.5C4H4O4 · H2O
Molecular Weight: 420.46
MDL Number: MFCD11045919
Linear Formula: C19H24N2O4 · 0.5C4H4O4 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F9552-10MG 10 mg
 $243.00
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45-F9552-50MG 50 mg
 $838.00
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts F9552-10MG

 

assay >98% (HPLC)
color white to off-white
form solid
InChI 1S/2C19H24N2O4.C4H4O4.2H2O/c2*1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-3(6)1-2-4(7)8;;/h2*3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2H,(H,5,6)(H,7,8);2*1H2/b;;2-1+;;/t2*13-,19+;;;/m00.../s1
InChI key RATSWNOMCHFQGJ-TUYNVFRMSA-N
originator Novartis
Quality Level 100 
SMILES string O.O.OC(=O)C=CC(O)=O.COc1ccc(C[C@H](C)NC[C@@H](O)c2ccc(O)c(NC=O)c2)cc1.COc3ccc(C[C@H](C)NC[C@@H](O)c4ccc(O)c(NC=O)c4)cc3
solubility DMSO: soluble 20 mg/mL
  H2O: insoluble
Application: Formoterol fumarate dihydrate has been used:
• as ß2-adrenergic agonist, to determine whether ß2-adrenergic receptor signaling was sufficient to induce up-regulation of select gene transcripts
• as a ß2-adrenergic receptor agonist and a long term bronchodilator
• as ß2-adrenergic receptor (ß2AR) agonist to recover renal function in ischemia-reperfusion injury (IRI) in mice
Biochem/physiol Actions: β2-Adrenoreceptor agonist.
Biochem/physiol Actions: Formoterol fumarate dihydrate can be used along with budesonide to treat asthma.
Features and Benefits: This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
UNSPSC 12352200

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