Adenosine 5′-triphosphate (ATP) disodium salt hydrate

SIGMA/FLAAS - vial of ~1 mg ATP

Synonym: ATP disodium hydrate

CAS Number: 34369-07-8
Empirical Formula (Hill Notation): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
Molecular Weight: 551.14 (anhydrous basis)
EC Number: 213-579-1
MDL Number: MFCD00150755
Linear Formula: C₁₀H₁₄N₅O₁₃P₃Na₂ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-FLAAS-1VL	1 vial	$71.90 1/EA	Add To Favorites
45-FLAAS-5VL	5 vials	$210.00 1/EA	Add To Favorites
45-FLAAS-10VL	10 vials	$375.00 1/EA	Add To Favorites

ATP is hydrolyzed and light is emitted when firefly luciferase catalyzes the oxidation of D-luciferin. Reaction (1) is reversible and the equilibrium lies far to the right. Reaction (2) is essentially irreversible. When ATP is the limiting reagent, the light emitted is proportional to the ATP present.

Properties
Descriptions
Safety Info.
Basic Data

assay	≥90%
biological source	bacterial (Corynebacterium sp)
form	lyophilized powder
InChI	1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key	NTBQNWBHIXNPRU-MSQVLRTGSA-L
packaging	vial of ~1 mg ATP
Quality Level	200
SMILES string	Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
solubility	water: soluble, clear, colorless (1 vial + 0.1 mL)
storage temp.	−20°C

Application:	Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been: • used as a standard to measure ATP by bioluminescence method • used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β • used as a standard in ATP colorimetric assay
Biochem/physiol Actions:	Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.
Biochem/physiol Actions:	Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.
Biochem/physiol Actions:	P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems
Packaging:	1 vial in glass bottle
Preparation Note:	Each vial contains ~1.2 mg of Na₂ATP • 3H₂O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.
Preparation Note:	Prepared to be substantially vanadium-free.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2

Purity	≥90%
Storage Temp.	−20°C
UNSPSC	12352202

To Order From a Quote