L-Glutamine–Penicillin–Streptomycin solution
SIGMA/G1146 - with 200 mM L-glutamine, 10,000 U penicillin and 10 mg steptomycin/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture
Synonym: Pen/Strep; Penicillin/
MDL Number: MFCD00283636
Product Type: Chemical
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| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| biological source | synthetic |
| form | liquid |
| impurities | endotoxin, tested |
| mode of action | cell wall synthesis | interferes |
| protein synthesis | interferes | |
| product line | BioReagent |
| Quality Level | 300  |
| shipped in | dry ice |
| sterility | 0.1 μm filtered |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Used to reduce or eliminate bacterial contamination in cell, especially primary cell, cultures. Recommended for use in cell culture applications at 10 ml/L. |
| Biochem/physiol Actions: | Mode of Action: Glutamine is essential as an energy source for most mammalian cells in culture because of its amino acid carbon skeleton. Penicillin acts by inhibiting bacterial cell wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| Other Notes: | Formulated with 200 mM |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P272 - P280 - P284 - P302 + P352 - P304 + P340 + P312 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 23-36/37-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352207 |