Synonym: 4′,7-Dihydroxy 6-methoxyisoflavone 7-O-glucoside; 4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-6-methoxy-; Glycitein 7-O-β-glucoside
CAS Number: 40246-10-4
Empirical Formula (Hill Notation): C22H22O10
Molecular Weight: 446.40
MDL Number: MFCD00800711; MFCD00800711
Linear Formula: C22H22O10
Product Type: Chemical
| assay |
≥98% (HPLC) |
| biological source |
plant (Pueraria thunbergianaI) |
| color |
white to faint beige |
| form |
powder |
| InChI |
1S/C22H22O10/c1-29-15-6-12-14(30-9-13(18(12)25)10-2-4-11(24)5-3-10)7-16(15)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1 |
| InChI key |
OZBAVEKZGSOMOJ-MIUGBVLSSA-N |
| mp |
203 - 204 °C ((397 - 399 °F )) |
| Quality Level |
100  |
| SMILES string |
O=C1C2=CC(OC)=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C2OC=C1C4=CC=C(O)C=C4 |
| solubility |
10 mg, clear, colorless to faintly yellow |
| storage temp. |
room temp |
| technique(s) |
HPLC: suitable |
| Application: |
- The antioxidant Glycitin protects against intervertebral disc degeneration through antagonizing inflammation and oxidative stress in nucleus pulposus cells.: This study highlights Glycitin′s therapeutic potential in mitigating intervertebral disc degeneration by counteracting inflammatory and oxidative processes, demonstrating its viability as a bioactive compound for degenerative diseases (Zhao W et al., 2023
 ).
- Spectrum-effect relationship study to reveal the pharmacodynamic substances in Flos Puerariae-Semen Hoveniae medicine pair for the treatment of alcohol-induced liver damage.: Analyzes the pharmacological effects of herbal components, including Glycitin, targeting liver damage recovery, illustrating the compound′s therapeutic relevance in traditional and modern medical applications (Zhang H et al., 2023 ).
|
| Biochem/physiol Actions: |
Glycitin is a soy isoflavone in the glucoside form. A rat model study demonstrated glycitin to be effective in preventing bone loss and reversing the unfavorable changes of lipid metabolism in this model. |
| General description: |
Glycitin is an isoflavonoid recently found in flowers of Pueraria thunbergianaI. Glycitin can be modified into the metabolite glycitein which has anti-inflammatory properties. |
| Other Notes: |
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
| Packaging: |
Bottomless glass bottle. Contents are inside inserted fused cone. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| mp |
203 - 204 °C ((397 - 399 °F )) |
| Storage Temp. |
room temp |
| UNSPSC |
12352201 |
