D-(+)-Galactosamine hydrochloride
SIGMA/G1639 - BioReagent, suitable for cell culture
Synonym: 2-Amino-2-deoxy-D-galactopyranose hydrochloride; D-Chondrosamine hydrochloride
CAS Number: 1772-03-8
Empirical Formula (Hill Notation): C6H13NO5 · HCl
Molecular Weight: 215.63
EC Number: 217-198-1
MDL Number: MFCD00135830
Linear Formula: C6H13NO5 · HCl
Product Type: Chemical
| assay | ≥99% |
| biological source | fish cartilage (shark) |
| impurities | Glucosamine, essentially free |
| InChI | 1S/C6H13NO5.ClH/c7-3(1-8) |
| InChI key | CBOJBBMQJBVCMW-NQZVPSPJSA |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| shipped in | ambient |
| SMILES string | Cl.N[C@@H](C=O)[C@@H](O)[ |
| solubility | water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | D-(+)-Galactosamine hydrochloride has been used to: • induce livery injury • inflammatory liver injury • acute liver failure (ALF) in mice |
| Biochem/physiol Actions: | Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF). |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 100 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |

