Galanthamine hydrobromide from Lycoris sp.
SIGMA/G1660 - ≥94% (HPLC)
Synonym: Galantamine hydrobromide
CAS Number: 1953-04-4
Empirical Formula (Hill Notation): C17H21NO3 · HBr
Molecular Weight: 368.27
EC Number: 217-780-5
MDL Number: MFCD00067672
Linear Formula: C17H21NO3 · HBr
Product Type: Chemical
| assay | ≥94% (HPLC) |
| biological source | plant (Ungeria victoris) |
| form | powder |
| InChI | 1S/C17H21NO3.BrH/c1-18-8- |
| InChI key | QORVDGQLPPAFRS-XPSHAMGMSA |
| mp | 270 °C |
| Quality Level | 100  |
| SMILES string | Br[H].COc1ccc2CN(C)CC[C@@ |
| solubility | DMSO: soluble 10 mg/mL, clear, colorless |
| water: soluble 20 mg/mL, clear, colorless | |
| storage temp. | −20°C |
| Application: | Galanthamine hydrobromide from Lycoris sp. has been used- • as an AChE (acetylcholinesterase) inhibitor and positive control in acetylcholinesterase assay performed to determine the activity of AChE • as a positive control in the screening of AChE inhibitors • as a positive control in AChE inhibitory assay performed to determine the AChE-inhibitory activities of pyrithione and related sulfur-containing pyridine N-oxides |
| Biochem/physiol Actions: | Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic. |
| General description: | Galanthamine hydrobromide is a derivative of galanthamine, which is an anticholinestrase alkaloid derived from genus Lycoris (Amaryllidaceae) or snowdrop. This compound is used for the treatment of Alzheimer’s disease (AD). |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 1544PSN1 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥94% (HPLC) |
| mp | 270 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352116 |