Gly-Pro-Arg-Pro

SIGMA/G1895 - ≥95% (HPLC)

Synonym: GPRP; Glycyl-Prolyl-Arginyl-Proline amide

CAS Number: 67869-62-9
Empirical Formula (Hill Notation): C₁₈H₃₁N₇O₅
Molecular Weight: 425.48
MDL Number: MFCD00133378
Linear Formula: C₁₈H₃₁N₇O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-G1895-5MG	5 mg	$138.00 1/EA		Add To Favorites
45-G1895-25MG	25 mg	$448.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
InChI	1S/C18H31N7O5/c19-10-14(26)24-8-2-5-12(24)15(27)23-11(4-1-7-22-18(20)21)16(28)25-9-3-6-13(25)17(29)30/h11-13H,1-10,19H2,(H,23,27)(H,29,30)(H4,20,21,22)/t11-,12-,13-/m0/s1
InChI key	WXPZDDCNKXMOMC-AVGNSLFASA-N
Quality Level	200
SMILES string	NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N2CCC[C@H]2C(O)=O
storage temp.	−20°C
UniProt accession no.	P02751
	P04937
	P11276

Amino Acid Sequence:	Gly-Pro-Arg-Pro
Application:	Gly-Pro-Arg-Pro (GPRP) has been used for the formation of crystal composed of GPRP and the 30kDa C-terminal fragment from the γ chain of fibrinogen (rFbgγC30), cloned and expressed in Pichia pastoris.
Biochem/physiol Actions:	Gly-Pro-Arg-Pro (GPRP) is capable of increasing free thrombin. Thus it can be utilized to make thrombin-degranulated platelets, which helps in studying platelet reactions.
Biochem/physiol Actions:	Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis (β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
Biochem/physiol Actions:	Inhibits fibrin polymerization.
General description:	Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the α chain of fibrin protein.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352209

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.