Glycitein
SIGMA/G2785 - ≥97% (HPLC)
Synonym: 4′,7-Dihydroxy-6-methoxyisoflavone; Glycetein
CAS Number: 40957-83-3
Empirical Formula (Hill Notation): C16H12O5
Molecular Weight: 284.26
MDL Number: MFCD00016679
Linear Formula: C16H12O5
Product Type: Chemical
| assay | ≥97% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C16H12O5/c1-20-15-6-11 |
| InChI key | DXYUAIFZCFRPTH-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | COc1cc2C(=O)C(=COc2cc1O)c |
| solubility | DMF: 1 mg/mL, clear, colorless to faintly yellow |
| storage temp. | −20°C |
| Application: | Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors. |
| Biochem/physiol Actions: | Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis. |
| Biochem/physiol Actions: | Glycitein possesses weak estrogenic activity than other soy isoflavones. |
| Packaging: | 10 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |