Glycine hydrochloride
SIGMA/G2879 - ≥99% (HPLC)
Synonym: Aminoacetic acid hydrochloride; Glycine HCl; Glycocoll hydrochloride; Aminoacetic acid; Aminoethanoic acid; Glycocoll
CAS Number: 6000-43-7
Empirical Formula (Hill Notation): C2H5NO2 · HCl
Molecular Weight: 111.53
EC Number: 227-841-8
MDL Number: MFCD00012872
Linear Formula: H2NCH2CO2H · HCl
Product Type: Chemical
ATR-IR Spectra for Aminoacetic acid.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G2879-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G2879-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G2879-1KG
| assay | ≥99% (HPLC) |
| concentration | ≤100% |
| form | powder |
| InChI | 1S/C2H5NO2.ClH/c3-1-2(4)5 |
| InChI key | IVLXQGJVBGMLRR-UHFFFAOYSA |
| mol wt | 111.53 |
| mp | 176-180 °C (lit.) |
| Quality Level | 300  |
| SMILES string | Cl.NCC(O)=O |
| solubility | water: 0.5 g/mL, clear, colorless |
| storage condition | (Tightly closed Dry) |
| storage temp. | room temp |
| technique(s) | immunohistochemistry: suitable |
| Application: | Glycine hydrochloride has been used as a component of Ag (silver)-stripping buffer for multiplex immunohistochemistry in mice tissues. |
| Application: | Glycine hydrochloride has been used: • in the preparation of glycine-HCl buffer • to elute serum immunoglobulins (IgGs) from the beads in order to check for the complete enrichment of core- and site-specific antibodies • to regenerate the sensor to elute the bound C-reactive protein (CRP) |
| Biochem/physiol Actions: | Glycine acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain. |
| Biochem/physiol Actions: | Glycine comprises a single carbon molecule, that is attached to the amino and a carboxyl group. Glycine hydrochloride (Gly·HCl) is capable of liquifying native chitosan and also helps in the preparation of regenerated chitosan membrane. It can serve as an osmoprotectant. Glycine can act as a flexible link in proteins and can also allow the formation of helices. Free glycine may have a protecting role in tissues against ischemia, hypoxia, and reperfusion.Glycine has been studied as a potential treatment for sepsis, arthritis, adult respiratory distress syndrome, and other inflammatory diseases. |
| Biochem/physiol Actions: | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
| General description: | Research area: Neuroscience |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 100, 500 g in poly bottle |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| RIDADR | UN 3261 8 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| mp | 176-180 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |