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GW0742

SIGMA/G3295 - ≥98% (HPLC)

Synonym: 4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid

CAS Number: 317318-84-6
Empirical Formula (Hill Notation): C21H17F4NO3S2
Molecular Weight: 471.49
MDL Number: MFCD07369423
Linear Formula: C21H17F4NO3S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G3295-1MG 1 mg
 $258.00
1/EA		 Add To Favorites
45-G3295-5MG 5 mg
 $879.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts G3295-1MG

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
InChI key HWVNEWGKWRGSRK-UHFFFAOYSA-N
mp 134.5-135.5 °C
originator GlaxoSmithKline
Quality Level 100 
SMILES string Cc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O
solubility DMSO: >5 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Biochem/physiol Actions: GW0742 is a highly selective PPARδ agonist.
Biochem/physiol Actions: GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 μM and 2 μM for PPARα and PPARγ, respectively.
Features and Benefits: This compound is featured on the Nuclear Receptors (PPARs)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Sold for research purposes under agreement from Glaxo­Smith­Kline
Packaging: 1, 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
mp 134.5-135.5 °C
Storage Temp. 2-8°C
UNSPSC 12352200

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