Trisialoganglioside-GT_1b from bovine brain

SIGMA/G3767 - lyophilized powder, ≥96% (TLC)

Synonym: Ganglioside GT_1b

CAS Number: 59247-13-1
MDL Number: MFCD00081622
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-G3767-1MG	1 mg	$304.00 1/EA		Add To Favorites
45-G3767-5MG	5 mg	$1160.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥96% (TLC)
form	lyophilized powder
InChI	1S/C88H157N5O44/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-56(107)92-37-51(45(101)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)124-80-66(113)65(112)70(54(42-98)127-80)129-82-69(116)77(136-87(84(120)121)35-46(102)57(89)72(132-87)61(108)49(105)38-94)71(55(43-99)128-82)130-79-60(93-44(3)100)75(63(110)52(40-96)125-79)131-81-68(115)76(64(111)53(41-97)126-81)135-86(83(118)119)34-47(103)59(91)74(134-86)67(114)78(117)137-88(85(122)123)36-48(104)58(90)73(133-88)62(109)50(106)39-95/h30,32,45-55,57-82,94-99,101-106,108-117H,4-29,31,33-43,89-91H2,1-3H3,(H,92,107)(H,93,100)(H,118,119)(H,120,121)(H,122,123)/b32-30+/t45?,46-,47-,48-,49?,50?,51?,52-,53-,54+,55-,57+,58+,59+,60-,61?,62?,63+,64+,65+,66+,67?,68-,69-,70+,71+,72+,73+,74+,75-,76+,77-,78?,79+,80+,81+,82+,86+,87+,88+/m0/s1
InChI key	NVNPEYQWKCQBBU-ADMXJUBYSA-N
Quality Level	200
SMILES string	N([C@@H]1[C@H](O[C@H]([C@H]([C@H]1O[C@H]5O[C@H]([C@H]([C@H]([C@@H]5O)O[C@@]6(O[C@H]([C@@H]([C@H](C6)O)N)C(O)C(O[C@@]7(O[C@H]([C@@H]([C@H](C7)O)N)C(O)C(O)CO)C(=O)O)O)C(=O)O)O)CO)O)CO)O[C@@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O[C@@]4(O[C@H]([C@@H]([C@H](C4)O)N)C(
solubility	DMSO: soluble
	ethanol: soluble
storage temp.	−20°C

Amino Acid Sequence:	Cer-Glc-Gal(NeuAc-NeuAc)-GalNAc-Gal-NeuAc
Analysis Note:	Homogeneous aqueous preparations can be obtained by suspending the compound in water, buffer or cell culture medium and sonicating briefly to facilitate the micelle formation.
Application:	Trisialoganglioside-GT1b from bovine brain has been used: • in high performance thin layer chromatography (HPTLC) • in membrane GM1 assays • as reference standards for TLC (thin layer chromatography) and as antigens for ELISA (enzyme-linked immunosorbent assay)
Biochem/physiol Actions:	Ganglioside marker for metastatic brain tumors. Modulates cellular differentiation; prevents glutamate neurotoxicity; inhibits mitogenesis stimulated by lectins such as Con A. Converted to GD_1b by bacterial and mammalian sialidases.
General description:	Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Packaging:	1, 5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥96% (TLC)
Storage Temp.	−20°C
UNSPSC	12352200

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