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10074-G5

SIGMA/G3798 - ≥98% (HPLC)

Synonym: Biphenyl-2-yl-(7-nitrobenzo[1,2,5]oxadiazol-4-yl)amine; N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-amine; N-[1,1′-Biphenyl-2-yl]-7-nitro-2,1,3-Benzoxadiazol-4-amine

CAS Number: 413611-93-5
Empirical Formula (Hill Notation): C18H12N4O3
Molecular Weight: 332.31
MDL Number: MFCD00576774
Linear Formula: C18H12N4O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G3798-5MG 5 mg
 $131.00
1/EA		 Add To Favorites
45-G3798-25MG 25 mg
 $542.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts G3798-25MG.

 

assay ≥98% (HPLC)
color red
form powder
InChI 1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H
InChI key KMJPYSQOCBYMCF-UHFFFAOYSA-N
Quality Level 100 
SMILES string [O-][N+](=O)c1ccc(Nc2ccccc2-c3ccccc3)c4nonc14
solubility DMSO: >10 mg/mL
storage temp. room temp
Biochem/physiol Actions: 10074-G5 is a c-Myc/Max interaction inhibitor.
Biochem/physiol Actions: 10074-G5 is a c-Myc/Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4 (#F3680), specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM). It was discovered that 10074-G5 binds to a different specific binding site (region) of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions.
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25-36/37/38
Safety Statements 26-45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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