(E)-Guggulsterone

SIGMA/G4923 - ≥95% (HPLC), powder

Synonym: (17E)-Pregna-4,17(20)-diene-3,16-dione

CAS Number: 39025-24-6
Empirical Formula (Hill Notation): C₂₁H₂₈O₂
Molecular Weight: 312.45
MDL Number: MFCD01310758; MFCD01310758
Linear Formula: C₂₁H₂₈O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-G4923-5MG	5 mg	$195.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	white to off-white
form	powder
functional group	ketone
InChI	1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
InChI key	WDXRGPWQVHZTQJ-AUKWTSKRSA-N
Quality Level	100
shipped in	ambient
SMILES string	CC=C1C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
solubility	DMSO: soluble 5 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.
Biochem/physiol Actions:	Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Symbol	GHS07
Signal word	Warning
Hazard statements	H335 - H412
Precautionary statements	P261 - P271 - P273 - P304 + P340 + P312 - P403 + P233 - P405
Hazard Codes	Xi
Risk Statements	37-52/53
Safety Statements	61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352205

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