Synonym: (4Z)-7-[(1R,2R,3S,5S)-5-([1,1′-Biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-4-heptenoic acid hydrochloride
CAS Number: 87248-13-3
Empirical Formula (Hill Notation): C30H40NO4Cl
Molecular Weight: 514.10
MDL Number: MFCD04113055
Linear Formula: C30H40NO4Cl
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
off-white |
| form |
solid |
| InChI |
1S/C30H39NO4.ClH/c32-27-21-28(35-22-23-15-17-25(18-16-23)24-11-5-3-6-12-24)26(13-7-1-2-8-14-29(33)34)30(27)31-19-9-4-10-20-31;/h1-3,5-6,11-12,15-18,26-28,30,32H,4,7-10,13-14,19-22H2,(H,33,34);1H/b2-1-;/t26-,27-,28-,30+;/m0./s1 |
| InChI key |
ZYOBZRTZRQKKNC-UGNABIHOSA-N |
| mp |
127-128 °C |
| originator |
GlaxoSmithKline |
| Quality Level |
100  |
| shipped in |
wet ice |
| SMILES string |
Cl.O[C@H]1C[C@H](OCc2ccc(cc2)-c3ccccc3)[C@H](CCC=C/CCC(O)=O)[C@H]1N4CCCCC4 |
| solubility |
H2O: ~16 mg/mL |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
Selective TP prostanoid receptor antagonist. Inhibits U-46619-induced contraction of guinea pig trachea with IC50=1.8 nM. |
| Features and Benefits: |
This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: |
This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Legal Information: |
Manufactured and sold under agreement from GlaxoSmithKline |
| Packaging: |
1, 5 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| mp |
127-128 °C |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
