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Gly-Gln monohydrate

SIGMA/G5149 - ≥97% (HPLC)

Synonym: Glycyl-L-glutamine

CAS Number: 172669-64-6
Empirical Formula (Hill Notation): C7H13N3O4 · H2O
Molecular Weight: 221.21
MDL Number: MFCD00150855
Linear Formula: C7H13N3O4 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G5149-1G 1 g
 $79.30
1/EA		 Add To Favorites
45-G5149-5G 5 g
 $281.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5149-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5149-5G

 

assay ≥97% (HPLC)
InChI 1S/C7H13N3O4.H2O/c8-3-6(12)10-4(7(13)14)1-2-5(9)11;/h4H,1-3,8H2,(H2,9,11)(H,10,12)(H,13,14);1H2/t4-;/m0./s1
InChI key KLFWVRQACSYLOH-WCCKRBBISA-N
Quality Level 300 
SMILES string O.NCC(=O)N[C@@H](CCC(N)=O)C(O)=O
storage temp. −20°C
Amino Acid Sequence: Gly-Gln
Application: Gly-Gln monohydrate has been used:
• as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture equine embryos
• as a supplement in DMEM/F-12 to culture cleaved horse embryos
• in the human tubal fluid (HTF) medium to study ammonium accumulation in commercially available embryo culture media during incubation and storage
General description: Glycyl-glutamine (gly-gln) is a dipeptide that is used as a substitute for glutamine in cell culture. Higher cell yields are obtained when this dipeptide is used instead of glutamine, where gly-gln affects substrate utilization and metabolism. Cell growth is higher as the concentrations of this dipeptide remain high, due to lower peptidase affinity.
General description: Glycyl-glutamine is a dipeptide form of L-glutamine. Gly-Gln dipeptide exhibits enhanced solubility and thermostability. Moreover, this compound rapidly hydrolyzes into glutamine and glycine following intravenous infusion. Glycine can protect myocardial cells from ischemic injury by preventing cellular membrane permeability. Furthermore, the supplementation of glycyl-glutamine dipeptide proves advantageous for myocardial preservation in rats, as it enhances cardiocyte energy metabolism and augments ATP and glutathione synthesis.
Packaging: 1, 5 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥97% (HPLC)
Storage Temp. −20°C
UNSPSC 12352209

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