(Z)-Guggulsterone
SIGMA/G5168 - ≥89% (HPLC), powder
Synonym: (17Z)
CAS Number: 39025-23-5
Empirical Formula (Hill Notation): C21H28O2
Molecular Weight: 312.45
MDL Number: MFCD01310757
Linear Formula: C21H28O2
Product Type: Chemical
| application(s) | forensics and toxicology veterinary |
| assay | ≥89% (HPLC) |
| color | light yellow |
| form | powder |
| impurities | ≤5.4% E-form |
| InChI | 1S/C21H28O2/c1-4-16-19(23 |
| InChI key | WDXRGPWQVHZTQJ-OSJVMJFVSA |
| Quality Level | 200  |
| SMILES string | [H][C@@]12CCC3=CC(=O)CC[C |
| solubility | DMSO: 5 mg/mL |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Biochem/physiol Actions: | (Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator. |
| Biochem/physiol Actions: | (Z)-Guggulsterone is an antagonist ligand for bile acid receptor. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 |
| Hazard Codes | Xi |
| Risk Statements | 37-38 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥89% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |