β-Glycerophosphate disodium salt hydrate
SIGMA/G5422 - ≤1.0 mol % L-α-isomer
Synonym: BGP; Glycerol 2-phosphate disodium salt hydrate
CAS Number: 154804-51-0
Empirical Formula (Hill Notation): C3H7Na2O6P · xH2O
Molecular Weight: 216.04 (anhydrous basis)
EC Number: 212-464-3
MDL Number: MFCD00149082
Linear Formula: (HOCH2)2CHOP(O)(ONa)2 · xH2O
Product Type: Chemical
| biological source | synthetic |
| form | powder |
| impurities | ≤0.1% Inorganic phosphorus |
| ≤1.0 mol % |
|
| InChI | 1S/C3H9O6P.2Na.H2O/c4-1-3 |
| InChI key | ROPZSVKNEIIIDE-UHFFFAOYSA |
| mp | 102-104 °C (lit.) |
| Quality Level | 300 ![]() |
| SMILES string | O.[Na+].[Na+].OCC(CO)OP([ |
| solubility | water: 50 mg/mL, clear, colorless |
| Analysis Note: | Low inorganic phosphate content. Mixtures of α- and β-glycerophosphate have historically been used in microbiological media but high levels of inorganic (free) phosphate has been associated with the irregular growth of bacteria and unwanted precipitates. |
| Application: | β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression. |
| Application: | Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering. |
| Application: | β-glycerophosphate is used in homegenization solutions for muscles extracts following fixation. |
| Packaging: | 25, 100, 500 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 102-104 °C (lit.) |
| UNSPSC | 12352201 |

