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GR 113808

SIGMA/G5918 - ≥98% (HPLC), solid

Synonym: 1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

CAS Number: 144625-51-4
Empirical Formula (Hill Notation): C19H27N3O4S
Molecular Weight: 393.50
MDL Number: MFCD00912901
Linear Formula: C19H27N3O4S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G5918-10MG 10 mg
 $215.00
1/EA		 Add To Favorites
45-G5918-50MG 50 mg
 $683.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to light pink
form solid
InChI 1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3
InChI key MOZPSIXKYJUTKI-UHFFFAOYSA-N
originator GlaxoSmithKline
Quality Level 200 
SMILES string Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13
solubility DMSO: >20 mg/mL
storage temp. 2-8°C
Application: GR 113808 has been used as a serotonin receptor 4 (5-HT4R) blocker to study its effects on the calcium (Ca2+) transients in rat ventricular cardiomyocytes. It has also been used as a 5-HT4R antagonist to study its effects on de novo enteric neurogenesis in post-embryonic zebrafish.
Biochem/physiol Actions: GR 113808 is a 5-HT4 serotonin receptor antagonist.
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Sold for research purposes under agreement from Glaxo­Smith­Kline
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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