Guanosine 3′,5′-cyclic monophosphate sodium salt

SIGMA/G6129 - ≥99% (HPLC), powder

Synonym: 3′,5′-Cyclic GMP monosodium salt; 3′,5′-cGMP-Na; Guanosine 3′,5′-cyclophosphate monosodium salt; cGMP; cyclic GMP

CAS Number: 40732-48-7
Empirical Formula (Hill Notation): C₁₀H₁₁N₅NaO₇P
Molecular Weight: 367.19
EC Number: 255-056-0
MDL Number: MFCD00038424
Linear Formula: C₁₀H₁₁N₅NaO₇P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G6129-25MG	25 mg	$64.50 1/EA	Add To Favorites
45-G6129-100MG	100 mg	$187.00 1/EA	Add To Favorites
45-G6129-250MG	250 mg	$331.00 1/EA	Add To Favorites
45-G6129-500MG	500 mg	$539.00 1/EA	Add To Favorites
45-G6129-1G	1 g	$927.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6129-25MG.

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% (HPLC)
color	white
form	powder
InChI	1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1
InChI key	KMPIYXNEROUNOG-GWTDSMLYSA-M
Quality Level	200
SMILES string	[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1
solubility	H₂O: 50 mg/mL
storage temp.	−20°C

Biochem/physiol Actions:	An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Features and Benefits:	This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the Phosphodiesterases and PKA & PKG pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	1 g in poly bottle
Packaging:	100, 250, 500 mg in poly bottle
Packaging:	25 mg in glass insert

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
Storage Temp.	−20°C
UNSPSC	41106305

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