Glycine sodium salt hydrate
SIGMA/G6761 - ≥99% (HPLC)
CAS Number: 207300-76-3
Empirical Formula (Hill Notation): C2H4NNaO2 · xH2O
Molecular Weight: 97.05 (anhydrous basis)
MDL Number: MFCD00150683
Linear Formula: H2NCH2CO2Na · xH2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6761-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6761-500G
| assay | ≥99% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C2H5NO2.Na.H2O/c3-1-2( |
| InChI key | CIJQGPVMMRXSQW-UHFFFAOYSA |
| mol wt | 97.05 g/mol (anhydrous basis) |
| mp | 197-201 °C (lit.) |
| Quality Level | 300  |
| SMILES string | [Na+].[H]O[H].NCC([O-])=O |
| technique(s) | electrophoresis: suitable |
| Application: | Glycine sodium salt hydrate has been used as a component of buffer for homogenization of whole muscle for protein extraction and in electrophoresis buffer. It has also been used as a neurotransmitter in immunohistochemical staining of Zebrafish spinal cord sections. |
| Biochem/physiol Actions: | Glycine serves as a neurotransmitter in the central nervous system. It aids in increasing the quality of sleep and neurological functions. It is essential for the regulation immune function, metabolism, growth and development. Glycine modulates intracellular Ca2+ levels and cytokines production. Studies have shown that glycine treatment effectively prevents organ transplantation failure by mitigating ischemia reperfusion injury caused by cold ischemic storage. Additionally, glycine treatment also enhances graft function during transplantation. A reduction in glycine levels is observed in obesity, type 2 diabetes (T2DM), and non-alcoholic fatty liver disease (NAFLDs). Glycine is degraded to serine by glycine serine hydroxymethyltransferase 1 in cytoplasm. |
| General description: | Research area: Neuroscience Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine. |
| Packaging: | 1 kg in poly drum |
| Packaging: | 100, 500 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| mp | 197-201 °C (lit.) |
| UNSPSC | 12352209 |