Genistein
SIGMA/G6776 - from Glycine max (soybean), ~98% (HPLC)
Synonym: 4′,5,7-Trihydroxyisoflavone; 5,7-
CAS Number: 446-72-0
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
EC Number: 207-174-9
MDL Number: MFCD00016952
Linear Formula: C15H10O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6776-10MG
| assay | ~98% (HPLC) |
| biological source | Glycine max (soybean) |
| form | powder |
| InChI | 1S/C15H10O5/c16-9-3-1-8(2 |
| InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA |
| mp | >280 °C |
| Quality Level | 200  |
| SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc |
| solubility | DMSO: soluble |
| ethanol: soluble | |
| storage temp. | −20°C |
| Application: | Genistein has been used: • as an anticancer agent to test its cytotoxicity in cervix adenocarcinoma cells • as a polyphenol to test its effect on reactive oxygen species in mitochondria from sperm • to test its radical scavenging effect on the UV irradiated in dermal and keloid fibroblasts |
| Biochem/physiol Actions: | Genistein has antioxidant functionality and is effective in quenching reactive oxygen species. It is beneficial to human health. |
| Biochem/physiol Actions: | Inhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. |
| Features and Benefits: | This compound is featured on the Met page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: | Genistein is a nutraceutical isoflavnoid from soybean and is a phytoestrogen. It is derived from genistin. |
| Packaging: | 5, 10 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ~98% (HPLC) |
| mp | >280 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |