L-Glutamine–Penicillin–Streptomycin solution
SIGMA/G6784 - L-glutamine 200 mM, streptomycin 10 mg/mL, penicillin 10,000 units, 0.1 μm filtered, BioReagent, suitable for cell culture
Synonym: Pen/Strep; Penicillin/
MDL Number: MFCD00283636
Product Type: Chemical
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| antibiotic activity spectrum | Gram-negative bacteria |
| Gram-positive bacteria | |
| biological source | synthetic |
| composition | |
| penicillin, 10,000 units | |
| streptomycin, 10 mg/mL | |
| description | stabilized |
| form | liquid |
| impurities | endotoxin, tested |
| mode of action | cell wall synthesis | interferes |
| protein synthesis | interferes | |
| product line | BioReagent |
| Quality Level | 300  |
| sterility | 0.1 μm filtered |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | This antibiotic solution is used to reduce or eliminate bacterial contamination in primary cell cultures. It is recommended for us at 10 mL/L. |
| Biochem/physiol Actions: | Mode of Action: The product acts in three ways: Glutamine is an essential energy source for most mammalian cells in culture due to its amino acid carbon skeleton. Penicillin inhibits bacterial cell wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding. Antimicrobial spectrum: This product acts against both gram-negative and gram-positive bacteria. |
| Other Notes: | This solution is formulated to contain 200 mM L-glutamine, 10,000 units of Penicillin and 10 mg/mL of streptomycin, solubilized in a proprietary buffer. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352207 |