Glycine
SIGMA/G7403 - BioXtra, ≥99% (titration)
Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll
CAS Number: 56-40-6
Empirical Formula (Hill Notation): C2H5NO2
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131; MFCD00008131
Linear Formula: NH2CH2COOH
Product Type: Chemical
| absorption | ≤0.04 at 260 in 1 M HCl at 1 M |
| ≤0.04 at 280 in 1 M HCl at 1 M | |
| anion traces | chloride (Cl-): ≤0.005% |
| sulfate (SO42-): ≤0.005% | |
| assay | ≥99% (titration) |
| cation traces | Al: ≤0.0005% |
| As: ≤0.00001% | |
| Ba: ≤0.0005% | |
| Bi: ≤0.0005% | |
| Ca: ≤0.001% | |
| Cd: ≤0.0005% | |
| Co: ≤0.0005% | |
| Cr: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Li: ≤0.0005% | |
| Mg: ≤0.0005% | |
| Mn: ≤0.0005% | |
| Mo: ≤0.0005% | |
| Na: ≤0.02% | |
| NH4+: ≤0.02% | |
| Ni: ≤0.0005% | |
| Pb: ≤0.0005% | |
| Sr: ≤0.0005% | |
| Zn: ≤0.0005% | |
| color | white |
| form | powder |
| ign. residue | ≤0.05% |
| impurities | Insoluble matter, passes filter test |
| InChI | 1S/C2H5NO2/c3-1-2(4)5/h1, |
| InChI key | DHMQDGOQFOQNFH-UHFFFAOYSA |
| loss | ≤0.05% loss on drying, HV, 20-26 °C |
| mp | 240 °C (dec.) (lit.) |
| pKa (25 °C) | (1) 2.35, (2) 9.60 |
| 2.35 | |
| product line | BioXtra |
| Quality Level | 200 ![]() |
| SMILES string | NCC(O)=O |
| solubility | 1 M HCl: 1 M, clear, colorless |
| technique(s) | electron microscopy: suitable |
| UV absorption | λ: 260 nm Amax: ≤0.04 |
| λ: 260 nm Amax: 0.003 | |
| λ: 260 nm Amax: 0.006 |
| Application: | Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling. |
| Biochem/physiol Actions: | Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. |
| Biochem/physiol Actions: | Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 100, 250 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (titration) |
| mp | 240 °C (dec.) (lit.) |
| UNSPSC | 12352209 |

