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Guanosine 3′,5′-cyclic monophosphate

SIGMA/G7504 - ≥98% (HPLC), powder

Synonym: cGMP; cyclic GMP

CAS Number: 7665-99-8
Empirical Formula (Hill Notation): C10H12N5O7P
Molecular Weight: 345.21
EC Number: 231-641-6
MDL Number: MFCD00070129
Linear Formula: C10H12N5O7P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G7504-5MG 5 mg
 $75.20
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45-G7504-25MG 25 mg
 $269.00
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45-G7504-100MG 100 mg
 $860.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G7504-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G7504-25MG

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)
InChI key ZOOGRGPOEVQQDX-UHFFFAOYSA-N
Quality Level 200 
SMILES string NC1=NC(=O)c2ncn(C3OC4COP(O)(=O)OC4C3O)c2N1
solubility 0.2 M NaHCO3: 50 mg/mL
storage temp. −20°C
Biochem/physiol Actions: A major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides.
Biochem/physiol Actions: An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Features and Benefits: This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox  and Cyclic Nucleotide  products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 25, 100 mg in poly bottle
Packaging: 5 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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