Sephadex® G-75
SIGMA/G75120 - Medium
Synonym: Gel filtration media; Gel filtration resin
CAS Number: 37224-29-6
MDL Number: MFCD02258932
Product Type: Chemical
| application(s) | life science and biopharma |
| bead diameter | 40-120 μm |
| compatibility | Cytiva |
| matrix active group | phase |
| Quality Level | 200 ![]() |
| swelling | 1 g swells to 12-15 mL gel |
| technique(s) | buffer exchange: suitable |
| Application: | Sephadex® G-75 has been used to purify low density lipoproteins (LDL) by gel filtration. |
| Application: | Sephadex® G-75 has been used to separate the products from the pepsin digest by gel filtration chromatography and to desalt low density lipoproteins (LDL) by gel filtration. |
| Features and Benefits: | • Enables rapid desalting, contaminant removal, and buffer exchange in a single step. • Ideal for buffer exchange and cleanup of large biomolecules with a molecular weight exceeding 80,000. • Features the highest exclusion limit of 80,000 within the Sephadex G-range. • Classic gel filtration resin. |
| General description: | Sephadex G-75 is widely used for desalting and buffer exchange. This gel filtration resin is created through the crosslinking of dextran with epichlorohydrin. Sephadex varies in its cross-linking level across different types, influencing its swelling capacity and molecular fractionation range. |
| General description: | Sephadex® G-75 is a gel filtration media used in gel filtration chromatography and protein chromatography. Sephadex® G-75 has been used to study cystatin of the mammalian brain, suggest candidates for development of novel oral or other anti-infective agents and to purify procoagulant metalloproteinase from rattlesnake venom. |
| Legal Information: | Sephadex is a registered trademark of Cytiva |
| Packaging: | 10, 50, 500 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 23151817 |

