Glucose-6-phosphate Dehydrogenase from baker’s yeast (S. cerevisiae)
SIGMA/G7877 - Type VII, ammonium sulfate suspension, ≥200 units/mg protein
Synonym: glucose-6-phosphate dehydrogenase (NADP+); G-6-P-DH; Zwischenferment
CAS Number: 9001-40-5
EC Number: 232-602-6
MDL Number: MFCD00081656
Product Type: Chemical
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| application(s) | diagnostic assay manufacturing |
| biological source | bakers yeast |
| form | ammonium sulfate suspension |
| mol wt | 128 kDa |
| Quality Level | 200  |
| solubility | water: soluble |
| specific activity | ≥200 units/mg protein |
| storage temp. | 2-8°C |
| technique(s) | cell based assay: suitable |
| type | Type VII |
| Application: | Glucose-6-phosphate dehydrogenase has been used in a study to investigate the effect of dehydroepiandrosterone on cell growth and mitochondrial function in TM-3 cells. Glucose-6-phosphate dehydrogenase has also been used in a study to investigate the incidence of apoptosis and transcript abundance in bovine follicular cells. Glucose-6-phosphate dehydrogenase is used to test ketose reductase activity in developing maize endosperm. |
| Biochem/physiol Actions: | Glucose-6-phosphate dehydrogenase catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolacetone as the first step in the pentose phosphate pathway. |
| General description: | Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration). |
| Other Notes: | One unit will oxidize 1.0 μmole of |
| Packaging: | 2000 units in serum bottle |
| Physical form: | Crystalline suspension in 3.2 M (NH4)2SO4 solution, pH 7.0 |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H334 |
| Precautionary statements | P261 - P284 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥200 units/mg protein |
| Storage Temp. | 2-8°C |
| Enzyme Commission (EC) Number | 1.1.1.49 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |