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GLP-1R agonist

SIGMA/G8048 - ≥98% (HPLC)

Synonym: 2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-; 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB); Compound 2

CAS Number: 281209-71-0
Empirical Formula (Hill Notation): C13H15Cl2N3O2S
Molecular Weight: 348.25
MDL Number: MFCD11521508
Linear Formula: C13H15Cl2N3O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G8048-5MG 5 mg
 $243.00
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45-G8048-25MG 25 mg
 $974.00
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assay ≥98% (HPLC)
color light brown-yellow
form powder
InChI 1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18)
InChI key GNZCSGYHILBXLL-UHFFFAOYSA-N
Quality Level 100 
SMILES string [S](=O)(=O)(C)c1nc2c(nc1NC(C)(C)C)cc(c(c2)Cl)Cl
solubility DMSO: ≥10 mg/mL
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: GLP-1R is a small molecule GLP-1 receptor agonist.
Biochem/physiol Actions: GLP-1R is a small molecule GLP-1 receptor agonist. GLP-1 receptor signaling is a predominant mechanism for regulating glucose homeostasis. This compound represents a unique non-peptide tool for studying the role of GLP-1 in both in vivo and in vitro diabetes and obesity models.
General description: Glucagon-like peptide-1 receptor (GLP-1R) agonist is a potential oral drug for modulating glucagon-like peptide (GLP)-1 in diabetic patients. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight.
Packaging: 5, 25 mg in glass bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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