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Gallamine triethiodide

SIGMA/G8134 - ≥98% (TLC), powder, muscarinic receptor antagonist

CAS Number: 65-29-2
Empirical Formula (Hill Notation): C30H60I3N3O3
Molecular Weight: 891.53
EC Number: 200-605-1
MDL Number: MFCD00011832
Linear Formula: C30H60I3N3O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-G8134-5G 5 g
$198.00
1/EA
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45-G8134-25G 25 g
$724.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G8134-25G

 

assay ≥98% (TLC)
form powder
InChI 1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9H3;3*1H/q+3;;;/p-3
InChI key REEUVFCVXKWOFE-UHFFFAOYSA-K
mp 235 °C (dec.) (lit.)
Quality Level 200 
SMILES string [I-].[I-].[I-].CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC
solubility ethanol: soluble
  H2O: 100 mg/mL
storage temp. 2-8°C
Application: Gallamine triethiodide has been used:
• as a relaxant for measuring spinal trigeminal nucleus recordings from single neurons.
• as an antagonist in neuroblastoma cells as M2 receptor
• to reduce eye movement during retinal surgery in rat

Biochem/physiol Actions: Gallamine triethiodide has anti-muscarinic effect. It is a competitive antagonist for the muscarinic receptor. Gallamine is regarded as neuromuscular blocking agent.
Biochem/physiol Actions: Muscle relaxant; allosteric muscarinic receptor antagonist with an order of potency of M2 > M1 = M4 > M3 = M5. Ligand for the peripheral anionic binding site of acetylcholinesterase.
Disclaimer: Hygroscopic
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Muscarinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 g in poly bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26-36-45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 235 °C (dec.) (lit.)
Storage Temp. 2-8°C
UNSPSC 12352116

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