L-Glutamine
SIGMA/G8540 - meets USP testing specifications, suitable for cell culture, 99.0-101.0%, from non-animal source
Synonym: (S)
CAS Number: 56-85-9
Empirical Formula (Hill Notation): C5H10N2O3
Molecular Weight: 146.14
EC Number: 200-292-1
MDL Number: MFCD00008044
Linear Formula: H2NCOCH2CH2CH(NH2)CO2H
Product Type: Chemical
FT-NMR Spectra for (S)-2,5-Diamino-5-oxopentanoic acid.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: G8540-100G
This image depicts SKU: G8540-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: G8540-25G
This image depicts SKU: G8540-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: G8540-1KG
This image depicts SKU: G8540-1KG
| agency | meets USP testing specifications |
| anion traces | chloride (Cl-): ≤0.020% |
| sulfate (SO42-): ≤0.020% | |
| application(s) | agriculture |
| assay | 99.0-101.0% |
| biological source | non-animal source |
| cation traces | As: ≤1 ppm |
| Fe: ≤10 ppm | |
| NH4+: ≤0.10% | |
| color | white |
| form | powder |
| functional group | amide |
| ign. residue | ≤0.10% |
| impurities | endotoxin, residual solvents, tested |
| InChI | 1S/C5H10N2O3/c6-3(5(9)10) |
| InChI key | ZDXPYRJPNDTMRX-VKHMYHEASA |
| loss | ≤0.30% loss on drying |
| mp | 185 °C (dec.) (lit.) |
| optical activity | [α]20/D 31.5 to 33.0°, c = 10 in 2 M HCl |
| [α]20/D 6.3 to 7.3°, c = 4 in water | |
| Quality Level | 300  |
| SMILES string | N[C@@H](CCC(N)=O)C(O)=O |
| solubility | H2O: 25 mg/mL |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Glutamine amino acid has been used: • as a component of the serum-free medium to culture mice cochlear organotypic cells. • as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F-12 (DMEM/F-12) medium for culturing mice seminiferous tubule segments. • as a supplement in Roswell Park Memorial Institute (RPMI) 1640 medium to culture human monocytic cell line. |
| Biochem/physiol Actions: | |
| Biochem/physiol Actions: | L-Glutamine or Glutamine powder serves as a precursor for the synthesis of peptides, proteins, nucleotides, purine, pyrimidine, amino sugars, and nucleic acids. It plays an important role in promoting and maintaining cellular functions. Many cells and tissues like the intestine, kidneys, neurons in the central nervous system (CNS), liver, and pancreatic β-cells utilize glutamine at higher levels for their functioning. Glutamine regulates acid-base homeostasis and catabolic signaling. Glutamine plays a vital role in nitrogen transport and maintains the cellular redox state.Glutamine provides the necessary nitrogen, carbon and the reducing equivalents required for cell growth and division during cell culture. L-glutamic acid aids the incorporation of NH4+ into biomolecules. |
| General description: | L-Glutamine is the most abundant amino acid in mammalian blood and tissues. It is vital for biochemical and cell culture research. It supports cell growth, metabolism, and protein synthesis. In cell culture, it ensures cell viability, proliferation, and antibody production. In biochemical studies, L-Glutamine aids in metabolic pathways, biomolecule synthesis, and cellular processes. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research  |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99.0-101.0% |
| mp | 185 °C (dec.) (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352209 |