Glycine

SIGMA/G8898 - suitable for electrophoresis, ≥99%

Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll

CAS Number: 56-40-6
Empirical Formula (Hill Notation): C₂H₅NO₂
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131
Linear Formula: NH₂CH₂COOH
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G8898-500G	500 g	$89.00 1/EA	Add To Favorites
45-G8898-1KG	1 kg	$148.00 1/EA	Add To Favorites

ATR-IR Spectra for Aminoacetic acid.

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G8898-500G

Properties
Descriptions
Safety Info.
Basic Data

absorption	≤0.15 at 280 at 1 M
anion traces	chloride (Cl^-): ≤70 ppm
assay	≥99%
cation traces	heavy metals (as Pb): ≤20 ppm
color	white to off-white
form	powder
functional group	amine
	carboxylic acid
impurities	≤0.01% Insoluble matter
InChI	1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key	DHMQDGOQFOQNFH-UHFFFAOYSA-N
mp	240 °C (dec.) (lit.)
pKa (25 °C)	(1) 2.35, (2) 9.60
	2.35
Quality Level	200
SMILES string	NCC(O)=O
solubility	H₂O: 200 mg/mL, clear, colorless to faintly yellow
storage temp.	room temp
technique(s)	electrophoresis: suitable
	western blot: suitable

Analysis Note:	Tested for use in electrode buffers for PAGE and in transfer buffers for Western blots.
Application:	• Glycine has been used for the preparation of gelatin composites scaffold. • It has been used in the elution buffer to extract protein using HiTrap protein G column. • It has been used in the SDS-sample, running and transfer buffers prepared for SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis) and western blotting.
Biochem/physiol Actions:	Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Features and Benefits:	• Suitable for Cell Biology and Biochemical studies • High-quality compound suitable for multiple research applications
General description:	Glycine is a molecule with pI of 6.7, which is similar to the pH of stacking gel. It has advantage of low mobility, hydrophobicity and it does not associate with proteins. Glycine is a component of Tris-glycine and Tris-glycine-SDS (sodium dodecyl sulfate) running buffers for polyacrylamide gel electrophoresis. Glycine is also a component of Towbin′s transfer buffer for Western blots.
General description:	Glycine, an achiral proteinogenic amino acid, serves diverse roles in biochemistry and physiology. As a non-essential, non-polar glucogenic amino acid, it acts as an inhibitory neurotransmitter in the central nervous system and co-agonist at NMDA receptors with glutamate. Serving as a precursor, glycine is a crucial building block for macromolecules, playing a vital role in cellular processes. In addition to its biological functions, glycine exhibits versatility in research applications. Its role as a biochemical reagent makes it valuable in assays and procedures, while its buffering capacity is essential in techniques like SDS-PAGE, Western Blotting, chromatography, and cell culture. Glycine′s zwitterionic nature makes it an effective buffer across various pH values, widely used in immunology research for buffer preparation in techniques such as Western Blotting. Compatible with enzymes, glycine is useful in enzymatic assays like lactate determination. Moreover, glycine contributes to buffer formulations for protein stabilization, pH control, and enzymatic reactions.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	500 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
mp	240 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352209

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