Anti-Glutamate Receptor NMDAR1 (NR1) antibody produced in rabbit
SIGMA/G8913 - affinity isolated antibody, buffered aqueous solution
Synonym: Anti-GluN1; Anti-MRD8; Anti-NDHMSD; Anti-NDHMSR; Anti-NMD-R1; Anti-NMDA1; Anti-NMDAR1; Anti-NR1
MDL Number: MFCD00282329
Product Type: Chemical
Immunohistochemistry
Rat cerebellum tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913).
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Rat cerebellum tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913).
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Immunohistochemistry
Rat cerebellum tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913). Shows a line of Purkinje cells labeled with Anti-NMDAR1.
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Rat cerebellum tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913). Shows a line of Purkinje cells labeled with Anti-NMDAR1.
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Immunohistochemistry
Rat hippocampus tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913).
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Rat hippocampus tissue stained with Rabbit Anti-Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913).
From Dr. Shai Shoham, Research Laboratory, Sarah Herzog Memorial Hospital, Jerusalem, Israel
Immunoblotting Synaptosomal membrane fraction of rat brain was separated on SDS-PAGE and probed with APA Glutamate Receptor NMDAR1 (NR1) (Cat. No. G8913). The antibody was developed with AlkPhos APA Rabbit IgG (Cat. No. A9919) and a NBT/BCIP substrate. Antibody dilution 1/2,000.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 116 kDa |
| packaging | antibody small pack of 25 μL |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:2,000 using extract of a rat brain synaptosomal fraction. |
| UniProt accession no. | Q05586  |
| Application: | Anti-glutamate receptor NMDAR1 (NR1) antibody can be used as a primary antibody in western blotting. It can also be used to identify NR1 from rat brain synaptosomal fraction by using immunoblotting. |
| Application: | Anti-Glutamate Receptor NMDAR1 (NR1) antibody produced in rabbit has been used in endogenous calmodulin co-immunoprecipitation and immunoprecipitation. |
| Biochem/physiol Actions: | N-methyl- |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | N-methyl- |
| General description: | NMDAR1 is a subunit of N-methyl D-aspartate (NMDA) receptor which is a subtype of glutamate-gated ion channels with high calcium permeability. NMDA receptors have unique voltage-dependent sensitivity to magnesium and are modified by glycine. It has a pivotal role in neuronal development, pathogenesis of acute and chronic neurodegenerative disorders, synaptic plasticity as well as memory acquisition and learning. Anti-glutamate receptor NMDAR1 (NR1) antibody can be used for studying the expression and function of NMDAR1 in different cell types and tissues as well as to compare its expression pattern with physiological functions or pathological conditions. Rabbit anti-glutamate receptor NMDAR1 (NR1) antibody reacts specifically with NMDAR1 (116kD) derived from rat brain. |
| Immunogen: | synthetic peptide corresponding to the C-terminal region of rat NMDAR1 (amino acids 918-938). This sequence is identical in mouse NR1, human NR1 (short and long forms), and rat NR1 isoforms NR1b, NR1c, and NR1f. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research |
| Physical form: | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |