D-Glutamine
SIGMA/G9003 - ≥98% (HPLC)
Synonym: D-2-Aminoglutaramic acid; D-Glutamic acid 5-amide
CAS Number: 5959-95-5
Empirical Formula (Hill Notation): C5H10N2O3
Molecular Weight: 146.14
MDL Number: MFCD00065607; MFCD00065607
Linear Formula: C5H10N2O3
Product Type: Chemical
| application(s) | cell analysis |
| assay | ≥98% (HPLC) |
| color | white |
| form | powder |
| InChI | 1S/C5H10N2O3/c6-3(5(9)10) |
| InChI key | ZDXPYRJPNDTMRX-GSVOUGTGSA |
| Quality Level | 100 ![]() |
| SMILES string | N[C@H](CCC(N)=O)C(O)=O |
| Application: | D-Glutamine has been used to study its role in conferring protection against acetaldehyde-induced disruption of barrier function in Caco-2 cell monolayer. |
| Biochem/physiol Actions: | Glutamine forms the central metabolite in amino acid transamination via a-ketoglutarate and glutamic acid. This amino acid is metabolized by different enzymes, such as glutaminase, present in liver, and glutamine synthetase, present in skeletal muscle. It is produced in the cytoplasm from other amino acids, predominantly from branched-chain amino acids and glutamate. It plays an essential role in ammonia metabolism and detoxification. Its skeletal muscle levels are significantly reduced post trauma, operation and inflammatory states. It servers as a prognostic marker in fatal sepsis during which its skeletal muscle levels are decreased by 90%. |
| General description: | Glutamine is a non-essential and the most abundant free amino acid present in the human body. It is an important component of proteins and is one of the 20 proteinogenic amino acids. It forms 5-6% of bound amino acids. |
| Other Notes: | Unnatural isomer of glutamine |
| Packaging: | 1, 5, 10 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352209 |

