Synonym: 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid; 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid; 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS Number: 25812-30-0
Empirical Formula (Hill Notation): C15H22O3
Molecular Weight: 250.33
EC Number: 247-280-2
MDL Number: MFCD00079335
Linear Formula: C15H22O3
Product Type: Chemical
| form |
powder |
| InChI |
1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17) |
| InChI key |
HEMJJKBWTPKOJG-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1 |
| Application: |
Gemfibrozil has been used to to study its effects on cell cycle progression in yeast. It has been used to study the effects of fibrates on cell proliferation and gene expression in human cell lines. |
| Biochem/physiol Actions: |
Gemfibrozil selectively increases Apolipoprotein A-I levels. In yeast cells, application of gemfibrozil delays the start of DNA replication. It is used as a therapeutic agent for dyslipidemia. |
| Features and Benefits: |
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| General description: |
Gemfibrozil is a fibric acid derivative and a hypolipidemic drug. Gemfibrozil serves as a ligand for PPARα (peroxisome proliferator-activated receptor α). |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Precautionary statements |
P264 - P270 - P301 + P312 + P330 - P501 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
36 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
