N-Glycolylneuraminic acid
SIGMA/G9793 - ≥95% (HPLC), semisynthetic
Synonym: Neu5Glc; NeuNGl
CAS Number: 1113-83-3
Empirical Formula (Hill Notation): C11H19NO10
Molecular Weight: 325.27
MDL Number: MFCD00057551
Linear Formula: C11H19NO10
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: G9793-25MG
This image depicts SKU: G9793-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G9793-10MG
| application(s) | metabolomics |
| assay | ≥95% (HPLC) |
| biological source | semisynthetic |
| color | white |
| form | powder |
| impurities | water (Karl Fischer) |
| InChI | 1S/C11H19NO10/c13-2-5(16) |
| InChI key | FDJKUWYYUZCUJX-AJKRCSPLSA |
| Quality Level | 200  |
| SMILES string | [H][C@]1(O[C@@](O)(C[C@H] |
| solubility | water: soluble 20 mg/mL |
| storage temp. | −20°C |
| suitability | suitable for LC-MS |
| technique(s) | LC/MS: suitable |
| Application: | N-Glycolylneuraminic acid has been used: • as a sugar in microtiter biofilm methodologic approach for the enhancement of biofilm formation • as a standard for the determination of sialic acids in the nervous system of silkworm and to find the variations of sialic acids among different developmental stages. • as a standard in the high-performance liquid chromatography (HPLC) analyses to detect the molecular species of sialic acid (Sia) species using 1,2-diamino-4,5-methylene |
| Biochem/physiol Actions: | N-Glycolylneuraminic acid (Neu5Gc) functions as an important tool for profiling anti-Neu5Gc antibodies and sialic acid-binding proteins. |
| Features and Benefits: | • Ideal for Metabolomics, Biochemical and Cell Biology research • Versatile and adaptable for wide variety of laboratory and research applications |
| General description: | N-Glycolylneuraminic acid (Neu5Gc) is a nonhuman sialic acid molecule synthesized in pigs but not in humans, that has a role as a mammalian metabolite and an antigen. This hydroxylated form of sialic acid, specifically N-acetylneuraminic acid, features a glycolyl substituent on nitrogen and a beta-configuration at the anomeric center. The biosynthesis of N-glycolylneuraminic acid involves the enzymatic activity of cytidine monophosphate-N-acetylneu In humans, the absence of endogenous production results from a gene mutation affecting CMP-Neu5Ac hydroxylase, the enzyme responsible for converting N-acetylneuraminic acid into Neu5Gc. However, Neu5Gc can accumulate in human cells through external ingestion from dietary sources like red meat and dairy products. N-Glycolylneuraminic acid is a versatile compound that finds application in cell biology, metabolomics and biochemical research |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Other Notes: | To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 25 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352201 |