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Calmodulin-Sepharose 4B

SIGMA/GE17-0529-01 - Cytiva 17-0529-01, pack of 10 mL

Synonym: Calmodulin Affinity Resin; Calmodulin-Sepharose

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-GE17-0529-01 1 pkg
$799.00
1/EA
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Cytiva-17-0529-01

 

average diameter 90 μm
cleaning in place 4-9
ligand calmodulin
manufacturer/tradename Cytiva 17-0529-01
matrix 4% agarose
packaging pack of 10 mL
particle size 45-165 μm
storage condition (20% Ehtanol)
storage temp. 2-8°C
working range 4-9
Analysis Note: To view the Certificate of Analysis for this product, please visit www.cytiva.com .
Features and Benefits: • For single-step purification of native calmodulin-binding proteins
• Suitable for tandem affinity purification (TAP) of protein complexes
• Purification of calmodulin-regulated proteins from all eukaryotic cells
General description: Calmodulin Sepharose 4B affinity media for purification of proteins with affinity for calmodulin, a highly conserved regulatory protein involved in many cellular processes in eukaryotic cells.

Calmodulin is a highly conserved regulatory protein found in all eukaryotic cells.This protein is involved in many cellular processes such as glycogen metabolism,cytoskeletal control, neurotransmission, phosphate activity and control of NAD?/NADP? Calmodulin binds proteins principally through their interactions with hydrophobic sites on its surface. These sites are exposed after a conformational change induced by the action of Ca2+ on separate Ca2+-binding sites. The binding of enzymes may be enhanced if the enzyme substrate is present and enzyme-substratecalmoldulin-Ca2+ complexes are particularly stable.
Legal Information: Sepharose is a trademark of Cytiva
Preparation Note: Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Storage Temp. 2-8°C
UNSPSC 41106500

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