CM Sepharose™ Fast Flow
SIGMA/GE17-0719-10 - Cytiva 17-0719-10, pack of 25 mL
Synonym: CM Sepharose FF; IEX resin; chromatography resin; gel; ion exchange resin; matrix; weak cation resin
Product Type: Chemical
| average diameter | 90 μm |
| cleaning in place | 2-14 |
| description | Ion Exchanger Type (value) |
| ligand | carboxymethyl |
| manufacturer/tradename | Cytiva 17-0719-10 |
| matrix | 6% cross-linked agarose |
| packaging | pack of 25 mL |
| particle size | 45-165 μm |
| suitability | suitable for bioprocess medium |
| working range | 4-13 |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Application: | CM Sepharose™ Fast FLow is part of the Sepharose™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. It is composed of crosslinked 6% Agarose beads, with carboxymethyl (CM) weak cation exchange groups. CM Sepharose™ Fast FLow has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols. Scale-up with CM Sepharose™ Fast FLow is straight forward and the medium is available in a range of pre-packed process development tools. As member of the BioProcess media range, CM Sepharose™ Fast FLow meets industrial demands with security of supply and comprehensive technical and regulatory support. |
| Features and Benefits: | • Well-proven weak cation exchanger developed for industrial downstream processes • Used extensively for capture and intermediate purification of a wide range of approved biopharmaceuticals • The industry standard for ion exchange chromatography during recent decades • High chemical stability allows for well proven CIP and sanitization protocols • The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool. |
| General description: | CM Sepharose™ Fast FLow is a weak cation exchanger based on the well established Sepharose™ Fast FLow ion exchange platform, extensively used for preparative protein separations in both research and industrial applications. |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 4 to 30 °C (20% Ethanol) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | NONH for all modes of transport |
| UNSPSC | 41106500 |