Butyl-s Sepharose™ 6 Fast Flow
SIGMA/GE17-0978-02 - Cytiva 17-0978-02, pack of 200 mL
Synonym: HIC purification matrix; chromatography resin; column packing; hydrophobic interaction chromatography polymer; weak hydrophobic resin
Product Type: Chemical
Butyl-S Sepharose 6 Fast Flow, 200 mL
| average diameter | 90 μm |
| cleaning in place | 2-14 |
| ligand | butyl-S |
| manufacturer/tradename | Cytiva 17-0978-02 |
| matrix | 6% cross-linked agarose |
| packaging | pack of 200 mL |
| particle size | 45-165 μm |
| suitability | suitable for bioprocess medium |
| working range | 3-13 |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Application: | Butyl-S Sepharose™ 6 Fast FLow is part of the Sepharose™ Fast FLow HIC platform, which has been an industrial standard for HIC chromatography during recent decades. Butyl-S Sepharose™ 6 Fast FLow is composed of cross-linked 6% Agarose beads modified with butyl groups via a thio-ether linkage. It will exhibit a different selectivity compared to Butyl Sepharose™ 4 Fast FLow and other HIC Sepharose™ Fast FLow products. This resin is designed for the binding and elution of relatively strong hydrophobic molecules at comparatively Low salt concentrations. Butyl?S Sepharose™ 6 Fast FLow is particularly useful during the initial stages of a separation process to remove the bulk of impurities without stringent requirements for conditioning of the sample (e.g. adjustment of pH, salt concentration etc.) Butyl-S Sepharose™ 6 Fast FLow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Butyl-S Sepharose™ 6 Fast FLow meets industrial demands with security of supply and comprehensive technical and regulatory support. |
| Features and Benefits: | • Binds and elutes relatively strong hydrophobic molecules at comparatively Low salt concentrations • The least hydrophobic medium in the well proven Sepharose™ Fast FLow HIC range • Purifies recombinant Hepatitis B virus surface antigen from CHO cells • Developed and optimized in cooperation with a process-scale manufacturer of biopharmaceuticals • The hydrophilic nature of the base matrix ensures Low levels of non-specific binding. |
| General description: | Butyl-S Sepharose™ 6 Fast FLow is the least hydrophobic medium in the Sepharose™ Fast FLow hydrophobic interaction chromatography (HIC) range and is particularly useful during the initial stages of a purification process to remove the bulk of impurities. |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 4 to 30 °C (20% Ethanol) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | UN1170 - class 3 - PG 3 - Ethanol, solution |
| UNSPSC | 41106500 |