Capto™ S ImpAct
SIGMA/GE17-3717-01 - Cytiva 17-3717-01, pack of 25 ml
Synonym: IEX resin; cation; chromatography matrix; column packing; ion exchange resin; mAb separation medium; monoclonal antibody polishing media; sulfonate
Product Type: Chemical
| avg. part. size | 50 μm (d50V) |
| capacity | binding capacity(>85 mg BSA/mL medium, >90 mg lysozyme/ml medium, >100 mg IgG/ ml medium) |
| cleaning in place | 4-12 |
| ligand | (-SO3) |
| manufacturer/tradename | Cytiva 17-3717-01 |
| matrix | high-flow agarose |
| working range | 3-14 |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Features and Benefits: | Capto S ImpAct is a strong cation exchange chromatography medium (resin) developed for intermediate purification and polishing of monoclonal antibodies (MAbs) and other biomolecules. • High binding capacity, > 100 mg MAb/mL medium. • Efficient aggregate removal at high load of monoclonal antibodies. • High-resolution intermediate purification and polishing based on the well-established Capto platform. • Flexibility of design thanks to a large operational window of flow rates and bed heights for easy optimization and scaling. • High productivity enabling cost-efficient manufacturing. • Security of supply and comprehensive regulatory support. |
| General description: | This chromatography medium is part of our platform of high-resolution media based on the Capto product line. The polymeric ligand, in combination with the attributes of the base matrix, gives this cation exchanger a high binding capacity. Furthermore, the small bead size enables high-resolution purifications. The high-flow characteristics of Capto media allows for excellent pressure-flow properties. The exceptional binding capacity and resolution of Capto S ImpAct, combined with the ability to run at high flow rates and bed heights, increase productivity and flexibility in process design. Capto S ImpAct is a BioProcess chromatography medium developed for large-scale purification of biopharmaceutical proteins. Based on the well-established Capto base matrix, it provides many opportunities for improved productivity and straightforward process development. Capto S ImpAct is available in a range of different bulk pack sizes and convenient prepacked formats for easy scale-up and process development. As a member of the BioProcess media range, Capto S ImpAct meets industrial demands with security of supply and comprehensive technical and regulatory support. |
| Legal Information: | Capto is a trademark of Cytiva |
| RIDADR | NONH for all modes of transport |
| UNSPSC | 23151817 |