HiScreen™ Capto™ Adhere
SIGMA/GE28-9269-81 - Cytiva 28-9269-81
Synonym: anion; chromatography cartridge; mAB resin; multimodal matrix; polishing media; prepacked column
Product Type: Chemical
| avg. part. size | 75 (d₅₀v is the median particle size of the cumulative volume distribution) |
| bed size | 7.7 mm × 100 mm |
| bed volume | 4.7 mL |
| cleaning | 2-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.) |
| column I.D. | 7.7 mm |
| description | Ion Exchanger Type (value) |
| ligand | N-benzyl-N-methyl ethanolamine |
| manufacturer/tradename | Cytiva 28-9269-81 |
| matrix | highly cross-linked agarose |
| packaging | pkg of 1 ea |
| parameter | 44 psi |
| suitability | suitable for bioprocess medium |
| working range | 3-12(pH interval where the medium can be operated without significant change in function.) |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Features and Benefits: | • Capto adhere is a multimodal anion exchanger for intermediate purification and polishing of monoclonal antibodies after the protein A capture step, giving the possibility to design a two-step chromatographic downstream process. • Prepacked, ready-to-use columns for convenient process development optimization. • 10 cm bed height of HiScreen columns is designed to allow method optimization and parameter screening. • Easily connected in series to achieve 20 cm bed height. • Small bed volume gives fast results and minimal sample/buffer consumption. • Reproducible results, scalable to BioProcess columns packed with the same resin using the same linear fluid velocity. |
| General description: | HiScreen Capto adhere columns are prepacked with Capto adhere ion exchange chromatography resins, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening. The small column volume of 4.7 mL and bed height of 10 cm make HiScreen columns excellent tools for method optimization, parameter screening, robustness testing, and convenient scale-up. Process fluid velocities can be applied, since the 10 cm bed height gives enough residence time and the results can then serve as basis for linear process scale-up. |
| Legal Information: | Capto is a trademark of Cytiva |
| Legal Information: | HiScreen is a trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 2 to 8 °C (20% Ethanol) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | NONH for all modes of transport |
| UNSPSC | 23151817 |