GST T2-2, Recombinant Rat
SIGMA/GS39
Synonym: glutathione S-transferase, theta 2
Product Type: Product-on-demand
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| assay | >95% (SDS-PAGE) |
| biological source | rat |
| concentration | 2.44 mg/mL |
| form | frozen liquid |
| mol wt | 23 kDa |
| Quality Level | 100  |
| recombinant | expressed in E. coli |
| specific activity | 13.18 |
| storage temp. | −70°C |
| Biochem/physiol Actions: | Glutathione S-transferase theta 2 (Gstt2) is an enzyme that in rats is encoded by the Gstt2 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. |
| General description: | using spectrophotometric determination of NADPH oxidation coupled to the glutathione peroxidase activity of GST T2-2 on cumene hydroperoxide (1.5 mM) in the presence of reduced glutathione (1 mM) in 100 mM NaPO4 (pH 7.0) at room temperature. |
| Preparation Note: | The enzyme should be used by the end-user customer within 1 year of receipt. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >95% (SDS-PAGE) |
| activity | specific activity: 13.18 |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |